The "file drawer" phenomenon: suppressing clinical evidence.
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منابع مشابه
Bias ( The “ File - Drawer Problem ” ) in Scientific Inference
Publication bias arises whenever the probability that a study is published depends on the statistical significance of its results. This bias, often called the file-drawer effect since the unpublished results are imagined to be tucked away in researchers’ file cabinets, is potentially a severe impediment to combining the statistical results of studies collected from the literature. With almost a...
متن کاملPublication Bias: The “File-Drawer” Problem in Scientific Inference
Publication bias arises whenever the probability that a study is published depends on the statistical significance of its results. This bias, often called the file-drawer effect because the unpublished results are imagined to be tucked away in researchers’ file cabinets, is a potentially severe impediment to combining the statistical results of studies collected from the literature. With almost...
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Evidence-based medicine is the golden bridge that connects the research world and the clinical domain. Systematic reviews are hailed as the foundation of this approach. They track down the best ‘available’ research in a particular area of interest, and systematically review them to generate a body of evidence that enables clinicians to adopt them into their daily practice. The important word in...
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1. Harsoor SS, Bhaskar SB. Learning research methodology: Revisiting the evidence. Indian J Anaesth 2016;60:619-21. 2. Dickersin K, Chalmers I. Recognizing, investigating and dealing with incomplete and biased reporting of clinical research: From Francis Bacon to the WHO. J R Soc Med 2011;104:532-8. 3. Rosenthal R. The file drawer problem and tolerance for null results. Psychol Bull 1979;86:638...
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It is estimated that half of all trials have never been published which can lead to patients being denied the most effective treatment and being exposed to unnecessary side effects. Furthermore the trial participants have been misinformed since the trial results have not contributed to the care of future patients. However the non-publication of trials is often not due to a deliberate decision ...
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عنوان ژورنال:
- CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
دوره 170 4 شماره
صفحات -
تاریخ انتشار 2004